Publications

2014

Calligaris, David, Diana Caragacianu, Xiaohui Liu, Isaiah Norton, Christopher J. Thompson, Andrea L. Richardson, Mehra Golshan, et al. “Application of Desorption Electrospray Ionization Mass Spectrometry Imaging in Breast Cancer Margin Analysis.” Proceedings of the National Academy of Sciences of the United States of America, September 22, 2014. doi:10.1073/pnas.1408129111.
Santagata, Sandro, Livia S. Eberlin, Isaiah Norton, David Calligaris, Daniel R. Feldman, Jennifer L. Ide, Xiaohui Liu, et al. “Intraoperative Mass Spectrometry Mapping of an Onco-Metabolite to Guide Brain Tumor Surgery.” Proceedings of the National Academy of Sciences of the United States of America 111, no. 30 (July 29, 2014): 11121–26. doi:10.1073/pnas.1404724111.
Auclair, Jared R., Joseph P. Salisbury, Joshua L. Johnson, Gregory A. Petsko, Dagmar Ringe, Daryl A. Bosco, Nathalie Y. R. Agar, Sandro Santagata, Heather D. Durham, and Jeffrey N. Agar. “Artifacts to Avoid While Taking Advantage of Top-down Mass Spectrometry Based Detection of Protein S-Thiolation.” Proteomics 14, no. 10 (May 2014): 1152–57. doi:10.1002/pmic.201300450.

2013

Eberlin, Livia S., Isaiah Norton, Daniel Orringer, Ian F. Dunn, Xiaohui Liu, Jennifer L. Ide, Alan K. Jarmusch, et al. “Ambient Mass Spectrometry for the Intraoperative Molecular Diagnosis of Human Brain Tumors.” Proceedings of the National Academy of Sciences of the United States of America 110, no. 5 (January 29, 2013): 1611–16. doi:10.1073/pnas.1215687110.
Ji, Minbiao, Daniel A. Orringer, Christian W. Freudiger, Shakti Ramkissoon, Xiaohui Liu, Darryl Lau, Alexandra J. Golby, et al. “Rapid, Label-Free Detection of Brain Tumors with Stimulated Raman Scattering Microscopy.” Science Translational Medicine 5, no. 201 (September 4, 2013). doi:10.1126/scitranslmed.3005954.
Colbert, Christopher L., Nathalie Y. R. Agar, Pravindra Kumar, Mathew N. Chakko, Sangita C. Sinha, Justin B. Powlowski, Lindsay D. Eltis, and Jeffrey T. Bolin. “Structural Characterization of Pandoraea Pnomenusa B-356 Biphenyl Dioxygenase Reveals Features of Potent Polychlorinated Biphenyl-Degrading Enzymes.” PloS One 8, no. 1 (2013). doi:10.1371/journal.pone.0052550.
Liu, Xiaohui, Jennifer L. Ide, Isaiah Norton, Mark A. Marchionni, Maritza C. Ebling, Lan Y. Wang, Erin Davis, et al. “Molecular Imaging of Drug Transit through the Blood-Brain Barrier with MALDI Mass Spectrometry Imaging.” Scientific Reports 3 (2013). doi:10.1038/srep02859.
Gholami, Behnood, Isaiah Norton, Livia S. Eberlin, and Nathalie Y. R. Agar. “A Statistical Modeling Approach for Tumor-Type Identification in Surgical Neuropathology Using Tissue Mass Spectrometry Imaging.” IEEE Journal of Biomedical and Health Informatics 17, no. 3 (May 2013): 734–44.

2012

Rodriguez, Noah, Junzheng Yang, Kathleen Hasselblatt, Shubai Liu, Yilan Zhou, Jose A. Rauh-Hain, Shu-Kay Ng, et al. “Casein Kinase I Epsilon Interacts with Mitochondrial Proteins for the Growth and  Survival of Human Ovarian Cancer Cells.” EMBO Molecular Medicine 4, no. 9 (September 2012): 952–63. doi:10.1002/emmm.201101094.
Gholami, Behnood, Isaiah Norton, Allen R. Tannenbaum, and Nathalie Y. R. Agar. “Recursive Feature Elimination for Brain Tumor Classification Using Desorption Electrospray Ionization Mass Spectrometry Imaging.” Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 2012 (2012): 5258–61. doi:10.1109/EMBC.2012.6347180.
Eberlin, Livia S., Isaiah Norton, Allison L. Dill, Alexandra J. Golby, Keith L. Ligon, Sandro Santagata, R. Graham Cooks, and Nathalie Y. R. Agar. “Classifying Human Brain Tumors by Lipid Imaging with Mass Spectrometry.” Cancer Research 72, no. 3 (February 1, 2012): 645–54. doi:10.1158/0008-5472.CAN-11-2465.

2011

Gholami, Behnood, Nathalie Y. R. Agar, Ferenc A. Jolesz, Wassim M. Haddad, and Allen R. Tannenbaum. “A Compressive Sensing Approach for Glioma Margin Delineation Using Mass Spectrometry.” Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 2011 (2011): 5682–85. doi:10.1109/IEMBS.2011.6091375.
Eberlin, Livia S., Xiaohui Liu, Christina R. Ferreira, Sandro Santagata, Nathalie Y. R. Agar, and R. Graham Cooks. “Desorption Electrospray Ionization Then MALDI Mass Spectrometry Imaging of Lipid  and Protein Distributions in Single Tissue Sections.” Analytical Chemistry 83, no. 22 (November 15, 2011): 8366–71. doi:10.1021/ac202016x.
Huang, Jacob, Behnood Gholami, Nathalie Y. R. Agar, Isaiah Norton, Wassim M. Haddad, and Allen R. Tannenbaum. “Classification of Astrocytomas and Oligodendrogliomas from Mass Spectrometry Data Using Sparse Kernel Machines.” Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 2011 (2011): 7965–68. doi:10.1109/IEMBS.2011.6091964.
Agar, Nathalie Y. R., Alexandra J. Golby, Keith L. Ligon, Isaiah Norton, Vandana Mohan, Justin M. Wiseman, Allen Tannenbaum, and Ferenc A. Jolesz. “Development of Stereotactic Mass Spectrometry for Brain Tumor Surgery.” Neurosurgery 68, no. 2 (February 2011): 280–289; discussion 290. doi:10.1227/NEU.0b013e3181ff9cbb.

2010

Agar, Nathalie Y. R., James G. Malcolm, Vandana Mohan, Hong W. Yang, Mark D. Johnson, Allen Tannenbaum, Jeffrey N. Agar, and Peter M. Black. “Imaging of Meningioma Progression by Matrix-Assisted Laser Desorption Ionization  Time-of-Flight Mass Spectrometry.” Analytical Chemistry 82, no. 7 (April 1, 2010): 2621–25. doi:10.1021/ac100113w.
Jiang, Xiuli, Yi Yu, Hong Wei Yang, Nathalie Y. R. Agar, Laura Frado, and Mark D. Johnson. “The Imprinted Gene PEG3 Inhibits Wnt Signaling and Regulates Glioma Growth.” The Journal of Biological Chemistry 285, no. 11 (March 12, 2010): 8472–80. doi:10.1074/jbc.M109.069450.
Karabacak, N. Murat, Michael L. Easterling, Nathalie Y. R. Agar, and Jeffrey N. Agar. “Transformative Effects of Higher Magnetic Field in Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.” Journal of the American Society for Mass Spectrometry 21, no. 7 (July 2010): 1218–22. doi:10.1016/j.jasms.2010.03.033.
Eberlin, Livia S., Allison L. Dill, Alexandra J. Golby, Keith L. Ligon, Justin M. Wiseman, R. Graham Cooks, and Nathalie Y. R. Agar. “Discrimination of Human Astrocytoma Subtypes by Lipid Analysis Using Desorption Electrospray Ionization Imaging Mass Spectrometry.” Angewandte Chemie (International Ed. in English) 49, no. 34 (August 9, 2010): 5953–56. doi:10.1002/anie.201001452.
Agar, Nathalie Y. R., Jane-Marie Kowalski, Paul J. Kowalski, John H. Wong, and Jeffrey N. Agar. “Tissue Preparation for the in Situ MALDI MS Imaging of Proteins, Lipids, and Small Molecules at Cellular Resolution.” Methods in Molecular Biology (Clifton, N.J.) 656 (2010): 415–31. doi:10.1007/978-1-60761-746-4_24.

2008

Wang, Qi, Joshua L. Johnson, Nathalie Y. R. Agar, and Jeffrey N. Agar. “Protein Aggregation and Protein Instability Govern Familial Amyotrophic Lateral Sclerosis Patient Survival.” PLoS Biology 6, no. 7 (July 29, 2008). doi:10.1371/journal.pbio.0060170.
Master, Emma R., Nathalie Y. R. Agar, Leticia Gomez-Gil, Justin B. Powlowski, William W. Mohn, and Lindsay D. Eltis. “Biphenyl Dioxygenase from an Arctic Isolate Is Not Cold Adapted.” Applied and Environmental Microbiology 74, no. 12 (June 2008): 3908–11. doi:10.1128/AEM.02928-07.

2007

Agar, Nathalie Y. R., Hong Wei Yang, Rona S. Carroll, Peter M. Black, and Jeffrey N. Agar. “Matrix Solution Fixation: Histology-Compatible Tissue Preparation for MALDI Mass  Spectrometry Imaging.” Analytical Chemistry 79, no. 19 (October 1, 2007): 7416–23. doi:10.1021/ac071460e.

2006

Werbowetski-Ogilvie, Tamra E., Nathalie Y. R. Agar, Roberta M. Waldkircher de Oliveira, Damien Faury, Jack P. Antel, Nada Jabado, and Rolando F. Del Maestro. “Isolation of a Natural Inhibitor of Human Malignant Glial Cell Invasion: Inter Alpha-Trypsin Inhibitor Heavy Chain 2.” Cancer Research 66, no. 3 (February 1, 2006): 1464–72. doi:10.1158/0008-5472.CAN-05-1913.

2005

Vaillancourt, Frederic H., Pascal D. Fortin, Genevieve Labbe, Nathalie M. Drouin, Zamil Karim, Nathalie Y. R. Agar, and Lindsay D. Eltis. “Molecular Basis for the Substrate Selectivity of Bicyclic and Monocyclic Extradiol Dioxygenases.” Biochemical and Biophysical Research Communications 338, no. 1 (December 9, 2005): 215–22. doi:10.1016/j.bbrc.2005.08.219.

2002

Ge, Yong, Frederic H. Vaillancourt, Nathalie Y. R. Agar, and Lindsay D. Eltis. “Reactivity of Toluate Dioxygenase with Substituted Benzoates and Dioxygen.” Journal of Bacteriology 184, no. 15 (August 2002): 4096–4103.